Ines de Santiago

Ines is working in the identification of genetic and epigenetic signatures that underly susceptability to breast cancer. Together with the lab of B. Ponder at the CRI, she is exploring to which extent genetic variation in the binding of ERα and co-factors (e.g. FOXA1, GATA3) influences susceptibility to breast cancer as well as response to therapy.


since 09/2012
Postdoctoral research at Cancer Research UK Cambridge Research Institute.

2007 - 2011
PhD student at CSC-MRC, Imperial College London, Unted Kingdom. Advisors: Prof. Ana Pombo.

2006 - 2007
PhD program in Computational Biology, at Instituto Gulbenkian de Ciencias, Oeiras, Portugal.

2001 - 2006
Degree in Biochemistry. Faculty of Sciences, University of Lisbon, Portugal.


Ph.D in Computational Biology and Stem cell biology

Imperial College London, UK.

Degree in Biochemistry
Faculty of Sciences, University of Lisbon, Portugal.

Awards and fellowships

Individual Ph.D Fellowship (2006-2011) Awarded by Fundação para a Ciência e Tecnologia, Portugal.
Ines de Santiago

Ines de Santiago
Li Ka Shing Centre
Robinson Way
Cambridge, CB2 0RE, UK
p: +44 (0) 1223 769 739

Funded by CRUK logo Affiliated with Cambridge University


  1. de Santiago I, Brookes E, Hebenstreit D, Morris KJ, Carroll T, Lenhard B, Stock JK, Heidemann M, Eick D, Nozaki N, Kimura H, Lenhard B, Ragoussis J, Teichmann SA, Pombo A. Polycomb repression co-associates with a specific RNA polymerase II variant, and is important for metabolic gene regulation in embryonic stem cells. Cell Stem Cell. 2012 Feb 3;10(2):157-70.
  2. Eukaryotic gene regulation in three dimensions and its impact on genome evolution. Babu MM, Janga SC, de Santiago I, Pombo A. Curr Opin Genet Dev. 2008 Dec;18(6):571-82.