Systems genetics: a synthesis of genetics, genomics and phenomics
Systems genetics is born out of a synthesis of multiple fields: it integrates approaches of genetics, genomics, and "phenomics", that is our increased ability to get quantitative and detailed measurements on a broad spectrum of phenotypes.
Tumors are ideal objects of systems genetic analyses, because they contain many different genotypes, many different cellular phenotypes, ongoing clonal evolution, interactions with the organismal environment and between the cells within the tumour micro-environment. These interactions influence disease progression and outcome as well as the development of metastases and are of key importance for treatment decisions.
Together we will define the main unanswered questions in the field and identify the next key challenges: Which (computational or experimental) developments will drive the field forward in the next years?
We will soon upload a copy of the preliminary program.
- Each participant gives a "chalk talk" of 20 min plus 5 min for questions (chalk talk = no PowerPoint, pen and white-board only).
- At the end of each session two participants kick-start the general discussion by summarizing the main results of the talks.
Participation in this workshop is by invitation only.
The workshop will be held at The Francis Crick Institute, which is located right next to the King's Cross and St Pancras train stations in the middle of London
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