Inferring genetic architecture from perturbation maps
Design and Analysis of Single and Combinatorial Gene Perturbation Screens
Modern high-throughput screening approaches are key technologies at the forefront of genetic research. They make it possible to describe a biological response to thousands of experimental perturbations.
This workshop will focus on novel experimental and computational strategies to use perturbation screens for dissecting cellular regulatory networks and disease mechanisms. The participants are leading international scientists covering both theoretical and experimental approaches for phenotyping and a wide range of research areas, model organisms and experimental techniques.
Together we will define the main unanswered questions in the field and identify the next key challenges: Which (computational or experimental) developments will drive the field forward in the next years?
Programme
Each participant gives a talk of 15 min, followed by 5 min of questions. At the end of the talk, each participant answers the question: "What is the next big thing in my field?" At the end of each session two participants kick-start the general discussion by summarizing the main results of the talks.
The workshop starts on Thursday with lunch (12oo-13:30) and ends Saturday night, with general departure on Sunday morning. There will be an afternoon session on Sept 15 and two sessions on both Sept 16 and Sept 17.
Please download the preliminary programme.
Participants

Ahringer, Julie | University of Cambridge | UK | Exp |
Beerenwinkel, Niko | ETH Zurich | CH | Comp |
Beijersbergen, Roderick | NKI Amsterdam | NL | Exp |
Blomberg, Anders | University of Gothenburg | SE | Exp |
Boutros, Michael | DKFZ Heidelberg | DE | Exp |
Di Bernardo, Diego | Telethon Institute, Naples | IT | Comp |
Gentleman, Robert | Genentech | US | Comp |
Hatzigeorgiou, Artemis | BSRC Alexander Fleming | GR | Comp |
Holstege, Frank | Utrecht University | NL | Exp |
Huber, Wolfgang | EMBL Heidelberg | DE | Comp |
Ketteler, Robin | UCL LMCB | UK | Exp |
Lehner, Ben | EMBL-CRG Barcelona | ES | Exp |
Margalit, Hanah | The Hebrew University | IL | Comp |
Markowetz, Florian | CRUK Cambridge Research Institute | UK | Comp |
Mäurer, Andre | MPI-IB Berlin | DE | Exp |
Michoel, Tom | Freiburg Institute for Advanced Studies | DE | Comp |
Moreau, Yves | KU Leuven | BE | Comp |
Mulder, Klaas | CRUK Cambridge Research Institute | UK | Exp |
Myers, Chad | University of Minnesota | US | Comp |
Nelander, Sven | University of Gothenburg | SE | Comp/Exp |
Nijman, Sebastian | Research Center for Molecular Medicine | AT | Exp |
Pelkmans, Lucas | ETH Zurich | CH | Exp |
Saez-Rodriguez, Julio | EMBL-EBI | UK | Comp |
Spang, Rainer | University of Regensburg | DE | Comp |
Taipale, Jussi | Helsinki University | FI | Exp |
Tavernier, Jan | Ghent University | BE | Exp |
Tresch, Achim | LMU Munich | DE | Comp |
Vert, Jean-Philippe | Ecole de Mines, Paris | FR | Comp |
Wessels, Lodwyk | NKI | NL | Comp |
Wilson, Paul | GlaxoSmithKline | UK | Comp |
Zupan, Blaz | University of Ljubljana | SI | Comp |
Directions
The workshop will be held at Lucy Cavendish College, Lady Margaret Road, Cambridge, CB3 0BU, UK. Telephone: + 44 (0)1223 332 181
The closest airport is London Stansted, from where Cambridge can easily be reached by train (30min) or bus (50min). From the train or bus station it is quick cab ride to Lucy Cavendish College. Further directions can be found here or in this map:
Reimbursement
To get reimbursed for parts of your travel costs (up to a maximum amount), please fill out the payment form (or as .doc with comments) and the bank details form and send both until 1st Oct 2011 to Tania Smith (Cancer Research UK Cambridge Research Institute, Robinson Way, Cambridge CB2 0RE, UK. Email: tania.smith||cancer.org.uk)