Systems genetics: a synthesis of genetics, genomics and phenomics
Systems genetics is born out of a synthesis of multiple fields: it integrates approaches of genetics, genomics, and "phenomics", that is our increased ability to get quantitative and detailed measurements on a broad spectrum of phenotypes.
Tumors are ideal objects of systems genetic analyses, because they contain many different genotypes, many different cellular phenotypes, ongoing clonal evolution, interactions with the organismal environment and between the cells within the tumour micro-environment. These interactions influence disease progression and outcome as well as the development of metastases and are of key importance for treatment decisions.
Together we will define the main unanswered questions in the field and identify the next key challenges: Which (computational or experimental) developments will drive the field forward in the next years?
- Each participant gives a "chalk talk" of 20 min plus 5 min for questions (chalk talk = no PowerPoint, pen and white-board only).
- At the end of each session two participants kick-start the general discussion by summarizing the main results of the talks.
Participation in this workshop is by invitation only.
Confirmed participants include:
|Antal, Tibor||Univ of Edinburgh||UK|
|Graham, Trevor||Barts Cancer Institute, London||UK|
|Greenman, Christopher||University of East Anglia||UK|
|Lingjaerde, Ole Christian||Oslo University||NO|
|Markowetz, Florian||CRUK CI||UK|
|Martincorena, Inigo||WT Sanger Institute||UK|
|Morris, Quaid||University of Toronto||CA|
|Reimand, Juri||OICR Toronto||CA|
|Schwarz, Roland||BIMSB, Berlin||DE|
|Sers, Christine||Charite, Berlin||DE|
|Shah, Sobrab||BCCA, Vancouver||CA|
|Sottoriva, Andrea||ICR, London||UK|
|Taipale, Jussi||Karolinska Institute||SE|
|Van Loo, Peter||The Francis Crick Institute||UK|
|Vermeulen, Louis||Amsterdam Medical Center||NL|
|Voet, Thierry||KU Leuven||BE|
|Wedge, David||University of Oxford||UK|
|Yuan, Ke||University of Glasgow||UK|
The workshop will be held at Lucy Cavendish College, Lady Margaret Road, Cambridge, CB3 0BU, UK. Telephone: + 44 (0)1223 332 181
The closest airport is London Stansted, from where Cambridge can easily be reached by train (30min) or bus (50min). From the train or bus station it is quick cab ride to Lucy Cavendish College. Further directions can be found here or in this map:
The organizers offer rooms for all participants. However, we will not be able to contribute towards your travel costs.