Systems genetics: a synthesis of genetics, genomics and phenomics

Systems genetics is born out of a synthesis of multiple fields: it integrates approaches of genetics, genomics, and "phenomics", that is our increased ability to get quantitative and detailed measurements on a broad spectrum of phenotypes.

Systems Genetics

Tumors are ideal objects of systems genetic analyses, because they contain many different genotypes, many different cellular phenotypes, ongoing clonal evolution, interactions with the organismal environment and between the cells within the tumour micro-environment. These interactions influence disease progression and outcome as well as the development of metastases and are of key importance for treatment decisions.

Together we will define the main unanswered questions in the field and identify the next key challenges: Which (computational or experimental) developments will drive the field forward in the next years?


Final programme [PDF]


Bakal, Chris ICR UK
Brenton, James CRUK CI UK
Bova, G. Steven Univeristy of Tampere FI
Campbell, Peter WT Sanger Institute UK
Dumeaux, Vanessa McGill CA
Fitzgerald, Rebecca University of Cambridge UK
Graham, Trevor Barts Cancer Institute, London UK
Korbel, Jan EMBL DE
Lopez-Bigas, Nuria Barcelona ES
Marioni, John EBI UK
Markowetz, Florian CRUK CI UK
Moreau, Yves KU Leuven BE
Nelander, Sven Uppsala University SE
Pe'er, Dana Columbia University US
Posada, David University of Vigo ES
Raphael, Ben Brown US
Sers, Christine Charite, Berlin DE
Shah, Sobrab BCCA, Vancouver CA
Szczurek, Ewa Warsaw PL
Taipale, Jussi Karolinska Institute SE
Van Loo, Peter The Francis Crick Institute UK
Voet, Thierry KU Leuven BE
Wedge, David WT Sanger Institute UK
Yuan, Yinyin ICR UK



The workshop will be held at Lucy Cavendish College, Lady Margaret Road, Cambridge, CB3 0BU, UK. Telephone: + 44 (0)1223 332 181

The closest airport is London Stansted, from where Cambridge can easily be reached by train (30min) or bus (50min). From the train or bus station it is quick cab ride to Lucy Cavendish College. Further directions can be found here or in this map:

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The organizers will arrange accommodation (3 nights) for all participants. Unfortunately, we will not be able to contribute towards your travel costs.


Funded by CRUK

Date and venue

21-23 Sept 2015
Lucy Cavendish College
Cambridge, UK
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The organizers have reserved single rooms at Lucy Cavendish College, Cambridge, for three nights (Sun evening - Wed morning).


Participants organize their travel to Cambridge. We recommend to come in on Sunday evening and travel back on Wednesday afternoon/evening.
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Peter Van Loo
Crick webpage

Florian Markowetz


Tania Smith